Abstract: The article proposes an approach to analyzing the reliability of commercial banks using multilayer neural networks and Kohonen self‐organizing maps, and also conducted their approbation on the example of the Ukrainian banking system from 2014 to 2018 with breakdown into 3 periods. Based on the experiments, the best variants of the architecture of neural networks are revealed. It is found that solving the problem of assessing the reliability of commercial banks in the clustering formulation gives a better result than in the classification formulation. The conclusion that a rapid change in the conditions of functioning of a modern banking system makes inefficient the use of analytical models with rigidly prescribed coefficients is experimentally substantiated. The results of the research are of practical importance and can be used to identify potential partners in the banking sector of the economy